Encapsulated papillary carcinoma, apocrine type, of the breast.
نویسندگان
چکیده
The apocrine type of encapsulated papillary carcinoma (ECP-A), of the breast is a rare neoplasm and there are only eight cases reported to date. Herein, we report the ninth case. A 68-year-old Japanese woman presented with a left breast mass. The cytoplasm of the tumour cells showed positive immunostaining for GCDFP-15. Myoepithelial cells were absent within the papillary structures and at the periphery of the lesion. The clinical course of the patient was uneventful 11 months after surgery. We postulate that EPC-A belongs to the molecular apocrine type of breast carcinoma.
منابع مشابه
Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe?
Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...
متن کاملA case of intracystic apocrine papillary tumor: diagnostic pitfalls for malignancy.
Intraductal/intracystic papillary carcinoma (IPC) of the breast is defined as a malignant non-invasive papillary tumor arising from the ductal-lobular system. Based on the presence of myoepithelial cells in the cystic wall, IPC is distinguished from encapsulated papillary carcinoma (EPC). Here, we report a case of an intracystic apocrine papillary tumor in the breast of a 49-year-old woman. His...
متن کاملApocrine cysts of the breast: biomarkers, origin, enlargement, and relation with cancer phenotype.
Up to one-third of women aged 30-50 years have cysts in their breasts and are presumed to be at increased risk of developing breast cancer. Here we present an extensive proteomic and immunohistochemistry (IHC) study of breast apocrine cystic lesions aimed at generating specific biomarkers and elucidating the relationship, if existent, of apocrine cysts with cancer phenotype. To this end we comp...
متن کاملMETAGENOUS CARCINOMA OF THE BREAST: SECONDARY DEPOSIT OF PAPILLARY CARCINOMA OF THE THYROlD IN A BREAST WITH PRIMARY DUCTAL CARCINOMAA COlNClDENCE
Papillary carcinoma of the thyroid constitutes 80% of thyroid malignancies in adults. Females are affected at least twice as often as males. It metastasizes to distant sites very rarely, but to the cervical nodes quite often. Occasionally metastatic lymph node enlargement is the sole presenting feature. t.3.6.7 The tumor is slow growing and sometimes the patient has good survival even in s...
متن کاملUnusual Breast Malignancy: Correlation of MRI Findings with Pathologic Features
Most breast malignancies arise from epithelial elements and are categorized as carcinomas. IDC not otherwise specified (NOS) and ductal carcinoma in situ are common breast cancers and account for about 85% of breast cancers (1). Unusual breast malignancies may be broadly divided into ILC, well-differentiated subtypes of IDC, cancers of stromal origin, and metastatic neoplasms (2). Well-differen...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Malaysian journal of pathology
دوره 36 2 شماره
صفحات -
تاریخ انتشار 2014